Give those holiday leftovers new life with this simple, satisfying turkey sandwich. Layers of leftover turkey, creamy mayo, crisp lettuce, tomato, cheddar, and a bit of cranberry sauce are tucked between toasted bread for the perfect sweet and savory bite.

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Holly’s Recipe Highlights
- Flavor: Savory turkey, tangy cranberry, and creamy mayo come together for the ultimate leftover lunch.
- Prep Note: The easiest way to enjoy Thanksgiving leftovers with no cooking at all. Everything’s prepped and ready to layer.
- Swaps: No leftover turkey? Use pre-sliced deli turkey and your favorite cheese for a quick shortcut.

What You’ll Need:
- Bread: My family loves sturdy breads like hearty grain bread, ciabatta, rye, or sourdough. Wrap all the ingredients in crisp romaine lettuce for a lighter option.
- Turkey: Use sliced deli turkey or leftover sliced turkey breast. Add other deli meats like ham, chicken, or cotto salami for variety, or crispy bacon for some extra flavor.
- Cheese: Choose your cheese; cheddar will give it an extra bite, while mozzarella and provolone will add a milder flavor to the sandwich.
- Vegetables: Add crunch with lettuce, tomatoes, or cucumbers. For extra creaminess, try sliced avocado.
- Condiments: Mix mayo with pesto for a flavorful aioli, add a chipotle aioli for a smoky kick, or use honey mustard for a sweet and tangy twist.
- Variations: Layer in leftover stuffing or drizzle on some gravy to turn it into a hearty, indulgent meal.

More Turkey Sandwich Ideas
- Hot Open Face: Top slices of turkey on bread, crumble on some dressing, and smother in gravy, like this hot turkey sandwich.
- Turkey Reuben Panini: If you have a panini press, pile turkey, Swiss cheese, and sauerkraut on buttered rye bread slices, and cook to a golden, crispy crunch. Grilling in a skillet will work too. Serve this one with Thousand Island dressing on the side.
- Turkey Salad: Make an easy turkey salad recipe and fill croissants or toasted English muffins!

Storage and Leftovers
Wrap leftover sandwiches tightly and refrigerate up to 1 day for the best texture. Freezing leftovers is not recommended once assembled, but you can freeze leftover turkey for up to 4 months!
Perfect Post Holiday Recipes
Did you enjoy this Turkey Sandwich? Leave us a rating and comment below!

Equipment
Ingredients
- 4 slices wheat bread
- 4 tablespoons mayonnaise
- 2 ounces cheddar cheese sliced, provolone or mozzarella
- 1 medium tomato sliced
- 4 leaves lettuce
- 6-8 slices deli sliced turkey or 4 slices leftover turkey
- ¼ cup cranberry sauce
Instructions
- Lightly toast the bread.
- Spread mayonnaise on 2 of the slices of toasted bread.
- Top with cheese, turkey, lettuce, and tomatoes. Season with salt & pepper if desired.
- Spread remaining slices of bread with cranberry sauce and top sandwich.
- Cut in half and serve.
Notes
Nutrition Information
Nutrition information provided is an estimate and will vary based on cooking methods and brands of ingredients used.
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Giving the information with clear details, such as the recipes and explanations. I really learnt a lots about the turkey sandwich. Thank you Holly!!!
Glad you enjoyed it, Steve! Thanks for trying our recipe.
I used your recipe for Roast Turkey Breast for these sandwiches and your other Turkey sandwiches. Yummy
So glad you enjoyed them, Sherry!