Pizza Grilled Cheese

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Pizza grilled cheese combines two of my all time favorite comfort foods: pizza and grilled cheese!

Grilled cheese is seriously the king of all sandwiches with toasty grilled bread and an ooey gooey cheesy middle.

In this pizza grilled cheese recipe, a classic grilled cheese sandwich is updated with pepperoni, pizza seasonings, and toppings then cooked to crispy cheesy perfection.

This is a sponsored conversation written by me on behalf of Sara Lee® Bread. The opinions and text are all mine.

Pizza Grilled Cheese Sandwich cut in half on a wooden board

There are few things more comforting than a grilled cheese sandwich and I’m excited to have partnered with Sara Lee® Artesano™ Bread for National Grilled Cheese Month to create my favorite version yet!

Dill pickle bacon grilled cheese has always topped my list of grilled cheese sandwiches and then I met the pizza grilled cheese.

A perfectly grilled cheese sandwich is a childhood staple that just brings me back… dipping them in tomato soup (is that weird?) or being in highschool and adding the best ever pickles on top and dipping them in ketchup (even more weird?).

Pizza is definitely another one of my all time fave foods so naturally marrying the two was bound to happen!

In this gourmet grilled cheese recipe a grilled cheese sandwich takes on all of the flavors of my favorite pepperoni pizza, but feel free to get creative and add in your own favorites toppings! The possibilities are endless; bacon, caramelized onions, olives, peppers or mushrooms, you can add them while it cooks!

A comfort food classic, this pizza grilled cheese whips up in under 15 minutes making it quicker than delivery and the perfect weeknight meal (or to curb a Friday night snack attack)!

Ingredients for Pizza Grilled Cheese Sandwich on a wood board

This grilled cheese recipe is a whole lot of pizza love in one bite. Layers and layers of cheese and pepperoni, seasonings and herbs. With all of that goodness packed in the middle, you’ll need a bread that can hold it all in without falling apart; Artesano Bread is the perfect bread for this recipe.

It’s so incredibly soft yet it’s sliced nice and thick meaning it can hold up to all of the toppings you’re going to pack inside of this sandwich! Sara Lee Artesano Bread has no high fructose corn syrup, no artificial flavors and no artificial colors plus it’s quite literally the perfect grilled cheese bread! It’s also available in Golden Wheat, which includes a touch of honey, olive oil and sea salt!

There’s something about this flavor combo that just speaks to me on a spiritual level!

Open Pizza Grilled Cheese Sandwich on a frying pan

How To Make Grilled Cheese

Grilled cheese is pretty easy to whip up, whether it’s for a weeknight dinner or quick meal. To truly achieve grilled cheese perfection, there’s a little more to it than slapping a piece of cheese between bread and frying it.

Start with a preheated pan and place your buttered bread in it, butter side down and start layering the toppings. You need to keep the heat low enough that the cheese gets all melty while the bread has a chance to get nice and golden without burning.

Once everything is nice and grilled, flip until the sandwich is golden on the other side and you’re ready to serve!

While you may have seen or heard of pizza grilled cheese before, I have a little trick that truly makes this the BEST grilled cheese you’ve ever had.  When I’m eating pizza, I’m all about the crispy pepperoni bits… and the golden cheese so it was mandatory to me that this grilled cheese had the crispy bits.  Once ready, I take the grilled cheese out of the pan and add a few slices of pepperoni & some mozza directly into the pan.  Place your sandwich on the cheese and let it cook until crispy cheesy good. If you’re using a non-stick pan, once it’s all crispy, it will not stick and you’ll have a crispy exterior that is seriously to die for! You’re welcome!

Pizza Grilled Cheese Sandwich with garnish

Stacks of Pizza Grilled Cheese Sandwich

Pizza Grilled Cheese Sandwich with garnish
4.97 from 26 votes
Review Recipe

Pizza Grilled Cheese

Prep Time 5 minutes
Cook Time 9 minutes
Total Time 14 minutes
Servings 2 servings
Pizza grilled cheese combines two of my all time favorite comfort foods: pizza and grilled cheese! Toasty grilled bread and an ooey gooey cheesy middle.


  • 4 slices Sara Lee Artesano Bread
  • 3 ounces mozzarella cheese shredded
  • 2 tablespoons pizza sauce plus extra for dipping
  • 2 tablespoons parmesan cheese shredded
  • 1 tablespoon basil thinly sliced
  • pinch dried oregano
  • 24 thin slices pepperoni about 1″ diameter
  • butter


  • 6 slices thin pepperoni
  • 2 tablespoons mozzarella cheese

Follow Spend with Pennies on Pinterest


  • Preheat a non-stick pan over medium heat.
  • Butter bread and place 2 slices butter side down in the pan. Top each slice with 1 tablespoon pizza sauce.
  • Layer cheese, 6 slices pepperoni, parmesan cheese, basil, oregano, remaining pepperoni and mozzarella. Top with remaining bread, butter side out.
  • Cook 3-4 minutes per side or just until golden.
  • Remove sandwich from the non-stick pan. Place 3 slices of pepperoni directly in the pan, top with 1 tablespoon mozzarella cheese. Place sandwich on top of cheese and let cook until crisp and crusted (about 1 minute). Serve.

Nutrition Information

Calories: 471, Carbohydrates: 30g, Protein: 28g, Fat: 25g, Saturated Fat: 11g, Cholesterol: 71mg, Sodium: 1354mg, Potassium: 250mg, Fiber: 2g, Sugar: 4g, Vitamin A: 515IU, Vitamin C: 1.1mg, Calcium: 499mg, Iron: 2.8mg

(Nutrition information provided is an estimate and will vary based on cooking methods and brands of ingredients used.)

Course Dinner
Cuisine American

Repin This Grilled Cheese Recipe

Pizza Grilled Cheese with text

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This is a sponsored conversation written by me on behalf of Sara Lee Bread. The opinions and text are all mine.

Pizza Grilled Cheese on a pan and on a wooden board with writing
About the author


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Holly is a wine and cheese lover, recipe creator, shopping enthusiast and self appointed foodie. Her greatest passion is creating in the kitchen and making deliciously comforting recipes for the everyday home cook!

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